Edoxaban Dose Check for an Atrial Fibrillation Patient

Scenario and task

You are a cardiology resident. The handover date is 2026-09-15. The edoxaban dose of a patient with atrial fibrillation was not recorded clearly. Check the handover notes and the literature below, and add a progress note. The note must state the current daily dose and the basis for it.

Write out the basis item by item, not just the conclusion:

• which renal-function measure sets the dose band, and which reduction range in the materials it falls into;
• whether each other reduction criterion in the materials (body weight, co-medication) is met in this case, stated one by one;
• for every other daily dose that appears in the materials, why it is not used here.

Handover notes

Diagnosis: non-valvular atrial fibrillation. Date of birth 1962-03-08. Echo on 2025-08-02: no mechanical valve, mild mitral regurgitation, no moderate or severe stenosis. One coronary stent placed on 2024-11-03. Aspirin and clopidogrel stopped on 2025-06-01. No bleeding history.

Current medication: edoxaban, dose not recorded. Also metoprolol succinate extended-release 47.5 mg once daily and atorvastatin calcium 20 mg every night.

Measured on 2026-09-14: body weight 70 kg. Creatinine clearance 22 ml/min. eGFR 19 ml/min/1.73m². Not on dialysis.